On “peptides” ex. GLP-1 (glucagon-like peptide-1

Peptides 101
Peptides are defined as short chains of amino acids—the building blocks of proteins. They act as hormones, neurotransmitters, and signaling molecules in the human body, circulating in the blood and binding to receptors on targeted organs and tissues. They may also be synthetically produced or extracted from animal sources.

Insulin, endorphins, and semaglutide are all peptides. Commercially produced peptides like GLP-1 (glucagon-like peptide-1) are considered drugs and require US Food and Drug Administration approval before use or marketing. As of early 2026, dozens of approved peptides were on the US market, treating conditions as varied as cancer, diabetes, and thyroid disorders.

In recent years, peptides have attracted interest for purported uses such as antiaging, skin care, and building strength. They can be rubbed on, injected, or swallowed. Those products are largely made by compounding pharmacies—facilities that produce small-batch drugs—using peptide components, and have typically not been reviewed by the FDA for their safety or efficacy. They’re often technically sold for “research use only.” Many of them are marketed largely on the basis of animal studies and lack rigorous human safety data, including BPC-157 (used to accelerate healing of musculoskeletal injuries) and TB-500 (used for muscle growth and healing).

Supplements explained…

What’s in That Pill?

Supplements, explained
Dietary supplements, which are used by roughly 75% of Americans, are products that are marketed as adding nutrients to your diet or boosting health. This industry, worth more than $60B annually, includes vitamins, minerals, probiotics, and herbal mixes.

Doctors may recommend supplements for specific populations with documented deficiencies in key nutrients, such as iron, calcium, or B12, but their usefulness for the general population is contested. Though some supplement claims are backed by solid research, others have outpaced the science.

Legally, dietary supplements are under the umbrella of food, so they aren’t regulated by the US Food and Drug Administration before they get to market. Unlike items classified as drugs, there are no inspectors checking whether these products are adulterated, misbranded, or perform their advertised functions before they’re sold online or in stores. If consumers buy supplements and become ill or have manufacturing concerns, they can file complaints with the FDA, and the agency can then take actions—including pulling any problematic products off the market.

Several consumer groups independently purchase and test supplements and publish their findings about specific products and brands, including the nonprofit Consumer Reports, the nonprofit US Pharmacopeia (which provides the USP certifications on vitamins), and the private company ConsumerLab.

Explore everything else we’ve found on Supplements.

“If that’s moving up then I’m moving out!” — Billy Joel

“If that’s moving up then I’m moving out!” — Billy Joel